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Single-cell ATAC Plus Gene Expression Reveals Differential Epigenetic Profiles of Macrophages Across Tissue Types

Download this work, presented by Active Motif Sr. Scientist Dr. Michael Garbati during the 2025 Annual Association of Immunologists conference. Using a multiomics approach, this work explores macrophage populations in distinct tissue types and their ATAC-Seq profile and gene expression from different tissues types and species. Previously this type of study relied on flow cytometry, a challenging method when working with tissues and oftentimes biased toward expression of cell surface markers.

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