激活剂 / 抑制剂

表观遗传研究的小分子物质

Active Motif has a collection of small-molecule epigenetic modulators (activators and inhibitors) that target changes to DNA methylation and chromatin remodeling proteins, such as histones. These include targets to DNA Methyltransferases (DNMTs), Histone Acetyltransferases (HATs), Histone Deacetylases (HDACs), Histone Methyltransferases (HMTs), Histone Demethylases (HDMs) and a distinct set of chromatin readers, bromodomains. As epigenetic dysregulation is implicated in many diseases, these modulators represent important tools for researchers in their assay development and drug discovery initiatives.

A list of the available activators and inhibitors for epigenetic research is shown below. Please click on the small molecule name to view complete product information.

 
Name Appl. Format Cat No. Price  
2'-Deoxy-5-fluorocytidine DNMT Inhibitor 250 mg 14108 ¥5,720 Add to Cart
50 mg 14109 ¥1,430 Add to Cart
5-Aza-2'-deoxycytidine (Decitabine) DNMT Inhibitor 50 mg 14100 ¥5,790 Add to Cart
10 mg 14101 ¥1,630 Add to Cart
5-Azacytidine DNMT Inhibitor 250 mg 14102 ¥1,300 Add to Cart
50 mg 14103 ¥650 Add to Cart
6-Thioguanine DNMT Inhibitor 1 g 14126 ¥1,820 Add to Cart
100 mg 14127 ¥650 Add to Cart
AK-7 SIRT2 Inhibitor 25 mg 14054 ¥3,770 Add to Cart
5 mg 14055 ¥1,040 Add to Cart
Apicidin HDAC Inhibitor 5 mg 14040 ¥4,030 Add to Cart
1 mg 14041 ¥1,170 Add to Cart
Arecoline hydrobromide ACAT1 Inhibitor 1 g 14132 ¥1,300 Add to Cart
250 mg 14133 ¥650 Add to Cart
AS-8351 KDM5B Inhibitor 25 mg 14112 ¥2,930 Add to Cart
5 mg 14113 ¥910 Add to Cart
Biotin-14-dATP N/A 1 mg 14138 ¥18,010 Add to Cart
200 µg 14139 ¥4,420 Add to Cart
BIX-01294 G9a/GLP Inhibitor 25 mg 14072 ¥6,830 Add to Cart
5 mg 14073 ¥1,630 Add to Cart