<< Back to Resources Home Page
Download Our Scientific Posters
Active Motif’s team of expert scientists travel around the world presenting data at conferences and scientific meetings. Here’s a list of some of our posters we presented for you to download if you weren’t able to attend.
A Universal Spike-In Normalization Strategy for CUT&RUN, CUT&Tag, and ATAC-Seq
This poster was presented at AACR 2024, describing the development of unique reagents for assay normalization. The use of Spike-In controls as a means of normalization in NGS based assays is shown to be not only useful, but in some cases necessary to detect true differences in gene expression or protein occupancy. Data is presented comparing Spike-In normalization with techniques using Drosophila nuclei.
Download the posterNovel KRAS-specific In-well Lysis ELISA for High Throughput Screening
This poster was presented at AACR 2023, describing the development of an activation state specific assay for KRAS, as well as Active Motif’s novel Single B-cell cloning technology for development of the recombinant antibody which provides the key specificity for the assay.
Download the posterNovel Epigenetics Technology for High-Throughput Processing of Limited Samples to Study Cancer Using Cavitation-based Pixelated Ultrasound and Tagmentation-indexing ChIP-Seq
This poster was presented at AACR 2023 and describes two novel technologies. One workflow applies pixelated ultrasound to enable sample preparation critical to a range of downstream applications. The second method presented is our new Tagmented, Indexed and Pooled ChIP-Seq (TIP-ChIP), a novel epigenetics assay to achieve high-throughput, multi-mark ChIP-Seq.
Download the posterNovel Epigenetics and Integrative Multiomics Methods for Sensitive Detection of Epigenetic Alterations: Potential to Understand Chromatin Control of Viral Infection
This poster was presented at the NIH Chromatin Control of Viral Infection Conference, 2022. The presentation features the incorporation of the PIXUL® Multi-Sample Sonicator as an intregal part of sample preparation in single-cell multiomic analysis via ATAC-Seq and RNA-Seq.
Download the posterTIP-ChIP: Tagmented, Indexed and Pooled ChIP-Seq to Generate High-Throughput, Multi-Target Results for Low Input Samples
Winner of a Reviewer’s Choice award, this poster was presented at the American Society for Human Genetics (ASGH), 2022. TIP-ChIP (Tagmented, Indexed, and Pooled ChIP-Seq) is a new method developed to rapidly complete ChIP-Seq on 96 samples for multiple epigenetic marks.
Download the posterAnchor-Based Bisulfite Sequencing (ABBS), Enrichment-Based Nucleotide-Resolution Approach to Measure DNA Methylation
Recently presented at Cold Spring Harbor, 2022, this poster presents Anchor-Based Bisulfite Sequencing (ABBS), developed as a method to determine DNA Methylation levels at single-base resolution, requiring up to 20X fewer reads than WGBS, with reduced sequencing depth and cost, and suitable for cell lines, tissue, and cfDNA sample types.
Download the posterNew High-Throughput Methods for the Epigenomic Characterization of Human Disease States
The new methods described in this poster, such as the PIXUL 96-well sonicator, transposase-assisted multiplex ChIP (TAM-ChIP), high-throughput ChIP, low cell number ChIP, and ChIP from FFPE tissues, are making it easier to characterize the epigenomic profiles associated with human diseases.
Download the posterEpi-Seq: Epigenome Landscape Mapping for Clinical and Drug Discovery Settings
This poster describes Epi-Seq, a complete experimental solution that will dramatically reduce the technical expertise and touch-time needed to perform ChIP-Seq, while also increasing consistency and throughput.
Download the posterNovel High-Throughput Tools for Detecting Age-Associated Epigenetic Changes in Liquid Biopsies
This poster demonstrates the applications of Active Motif’s high-throughput approaches to detect epigenetic alterations in human serum samples from healthy young and old individuals.
Download the poster