Recombinant CHD4 protein

Aliases: Chromodomain helicase DNA binding protein 4
Catalog No: 81385 Format: 20 µg ¥3,840 Add to Cart
Catalog No: 81685 Format: 1 mg ¥33,200 Add to Cart

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Expressed In: Baculovirus Protein Species: Human

Contents

A representative Technical Data Sheet (TDS) is provided here. Please refer to the lot-specific TDS you will receive with your order for the lot-specific buffer contents and protein concentration.

Background

CHD4 (Chromodomain Helicase DNA Binding Protein 4) is a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/ NuRD complex which participates in the remodeling of chromatin by deacetylating histones and is required for anchoring centrosomal pericentrin in both interphase and mitosis, for spindle organization and centrosome integrity.

Application Notes

This product was manufactured as described in Protein Details. Where possible, Active Motif has developed functional or activity assays for recombinant proteins. Additional characterization such as enzyme kinetic activity assays, inhibitor screening or other biological activity assays may not have been performed for every product. All available data for a given product is shown on the lot-specific Technical Data Sheet.

Protein Details

Recombinant CHD4 protein was expressed in a baculovirus expression system as the full length protein (accession number NP_001264.2) with a N-terminal FLAG tag. The molecular weight of the protein is 219.3 kDa.

References

Human

 
>Recombinant CHD4 protein

Recombinant CHD4 protein
7.5% SDS-PAGE with Coomassie staining
MW: 219.3 kDa
Purity: >90%

Storage

Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Guarantee

This product is guaranteed for 6 months from date of arrival.