Active Motif,
Tools to analyze nuclear function,
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重组蛋白 & 酶

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更多在试验中使用的生物学上相关的底物

Whether you are performing drug discovery screening, analyzing enzyme kinetics or monitoring changes in histone modifications, substrate selection is critical. Nucleosomes offer the advantage of providing a more biologically relevant substrate when compared to histone proteins alone or synthetic peptides.

HMT activity assay comparing recombinant nucleosomes and histone octamers as substrates.
HMT activity assay comparing recombinant nucleosomes and histone octamers as substrates.

(Click image to enlarge)

To best mimic cellular biology with your in vitro assay, use Active Motif’s Recombinant Nucleosomes. Active Motif’s pre-assembled Recombinant Nucleosomes save you time and effort by providing pre-assembled human nucleosomes. Each recombinant nucleosome is comprised of octamers of unmodified core histone proteins (H2A, H2B, H3 and H4) bound by DNA. These intact nucleosomes are ideal substrates for in vitro studies. Nucleosomes are available to study both Histone H3.1 and Histone H3.3 variants. Additionally, choose from unlabeled or biotin-labeled nucleosomes to give you flexibility in your experimental design.

 
Name Expressed In Format Cat No. Price  
Recombinant Histone Octamer (H3.1) E. coli 100 µg 31470 ¥5,727.50 Buy Now
1 mg 31870 ¥46,400 Buy Now
Recombinant Histone Octamer (H3.1) - biotinylated E. coli 50 µg 31471 ¥6,815 Buy Now
1 mg 31871 ¥50,750 Buy Now
Recombinant Histone Octamer (H3.3) E. coli 100 µg 31472 ¥5,727.50 Buy Now
1 mg 31872 ¥46,400 Buy Now
Recombinant Histone Octamer (H3.3) - biotinylated E. coli 50 µg 31473 ¥6,815 Buy Now
1 mg 31773 ¥50,750 Buy Now
Recombinant Mononucleosomes H3K4me1/H3K27ac - biotin Synthetic 10 µg 81003 ¥5,727.50 Buy Now
Recombinant Mononucleosomes H3K4me3/K27me3 - biotin Synthetic 10 µg 81005 ¥5,727.50 Buy Now
Recombinant Mononucleosomes H3K4me3/H3K27ac - biotin Synthetic 10 µg 81004 ¥5,727.50 Buy Now
Recombinant Mononucleosomes H3K9me3 (EPL) - biotinylated E. coli 20 µg 31555 ¥6,452.50 Buy Now
Recombinant Mononucleosomes H3K14ac (EPL) - biotin E. coli 20 µg 81001 ¥6,452.50 Buy Now
Recombinant Mononucleosomes H3K27ac - biotin  Synthetic 10 µg 81002 ¥5,727.50 Buy Now
Recombinant Mononucleosomes (H3.1) - biotinylated E. coli 20 µg 31467 ¥5,727.50 Buy Now
Recombinant Mononucleosomes (H3.3) - biotinylated E. coli 20 µg 31469 ¥5,727.50 Buy Now
Recombinant Mononucleosomes H3K9ac (EPL) - biotin E. coli 20 µg 81018 ¥6,453.50 Buy Now
Recombinant Mononucleosomes H3.3 (K27M) - biotin E. coli 20 µg 81006 ¥6,017.50 Buy Now
Recombinant Mononucleosomes H3.3 (G34L) - biotin E. coli 20 µg 81008 ¥6,017.50 Buy Now
Recombinant Mononucleosomes H3.3 (G34R) - biotin E. coli 20 µg 81009 ¥6,017.50 Buy Now
Recombinant Mononucleosomes H3.3 (G34V) - biotin E. coli 20 µg 81010 ¥6,017.50 Buy Now
Recombinant Mononucleosomes H3.3 (G34W) - biotin E. coli 20 µg 81011 ¥6,017.50 Buy Now
Recombinant Mononucleosomes H3.3 (K36M) - biotin E. coli 20 µg 81007 ¥6,017.50 Buy Now
Recombinant Mononucleosomes (H2A.Bbd) - biotinylated E. coli 20 µg 31556 ¥6,017.50 Buy Now
Recombinant Mononucleosomes (H2A.X) - biotinylated E. coli 20 µg 31582 ¥6,017.50 Buy Now
Recombinant Mononucleosomes (H2A.Z) - biotinylated E. coli 20 µg 31583 ¥6,017.50 Buy Now
Recombinant Mononucleosomes (TH2B) - biotinylated E. coli 20 µg 31557 ¥6,017.50 Buy Now
Recombinant Mononucleosomes H3K4me1 (EPL) - biotinylated E. coli 20 µg 31585 ¥6,452.50 Buy Now
Recombinant Mononucleosomes H3K4me3 (EPL) - biotinylated E. coli 20 µg 31584 ¥6,452.50 Buy Now
Recombinant Mononucleosomes H3K9me3 (EPL) E. coli 20 µg 31586 ¥6,017.50 Buy Now
Recombinant Polynucleosomes (H3.1) E. coli 20 µg 31466 ¥5,727.50 Buy Now
Recombinant Polynucleosomes (H3.3) E. coli 20 µg 31468 ¥5,727.50 Buy Now
Recombinant Polynucleosomes H3.3 (K27M) E. coli 20 µg 31562 ¥5,727.50 Buy Now
Recombinant Polynucleosomes H3.3 (G34L) E. coli 20 µg 31558 ¥5,727.50 Buy Now
Recombinant Polynucleosomes H3.3 (G34R) E. coli 20 µg 31559 ¥5,727.50 Buy Now
Recombinant Polynucleosomes H3.3 (G34V) E. coli 20 µg 31560 ¥5,727.50 Buy Now
Recombinant Polynucleosomes H3.3 (G34W) E. coli 20 µg 31561 ¥5,727.50 Buy Now
Recombinant Polynucleosomes H3.3 (K36M) E. coli 20 µg 31563 ¥5,727.50 Buy Now